All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the International Myeloma Foundation or HealthTree for Multiple Myeloma.
The Multiple Myeloma Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the Multiple Myeloma Hub cannot guarantee the accuracy of translated content. The Multiple Myeloma Hub and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.
The nuclear receptors (NRs) are a family of transcription factors that are regulated by steroids and related hormones, such as vitamin D3, thyroid hormone, and retinoids. NRs are good drug targets with internal pockets receptive to hydrophobic, drug-like molecules and well-characterized mechanisms that direct transcriptional coregulators to promoter elements.