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Symposium series | Integrating novel BCMA-directed therapies into clinical practice: Insights from real-world experience

By Jennifer Reilly

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Hermann EinseleHermann EinseleMaría-Victoria MateosMaría-Victoria MateosGordon CookGordon CookMarc-Andrea Bärtsch

Feb 3, 2026

Learning objective: After reading these articles, learners will be able to recall key clinical trial and real-world data for BCMA-directed therapies, and describe practical considerations for their integration, sequencing, and toxicity management in clinical practice.


On December 17, 2025, the Multiple Myeloma Hub held a virtual symposium, titled Integrating novel BCMA-directed therapies into clinical practice: Insights from real-world experience. The symposium was chaired by Hermann Einsele, with presentations from Marc-Andrea Bärtsch, Gordon Cook, and María-Victoria Mateos, and concluded with a panel discussion focused on practical, real-world considerations for the use, sequencing, and management of toxicities associated with B-cell maturation antigen (BCMA)-directed therapies in multiple myeloma. Explore each session below:

Symposium | Real-world insights and clinical experience with BCMA‑directed therapies

Symposium | Real-world insights and clinical experience with BCMA‑directed therapies

Real-world insights and clinical experience with B-cell maturation antigen (BCMA)-directed therapies for the treatment of multiple myeloma (MM) were presented by Gordon Cook at the recent Multiple Myeloma Hub symposium.

Symposium | BCMA-directed therapies in MM: Current applications and the evolving clinical landscape

Symposium | BCMA-directed therapies in MM: Current applications and the evolving clinical landscape

Current applications of B-cell maturation antigen (BCMA)-directed therapies in multiple myeloma (MM) and the evolving clinical landscape were described by Marc-Andrea Bärtsch during the recent Multiple Myeloma Hub symposium.

Symposium | Practical considerations when sequencing novel agents and managing AEs with BCMA-directed therapies

Symposium | Practical considerations when sequencing novel agents and managing AEs with BCMA-directed therapies

Key considerations when sequencing novel agents and managing adverse events with BCMA-directed therapies in relapsed/refractory multiple myeloma were discussed by the panel, chaired by Hermann Einsele, during the recent Multiple Myeloma Hub symposium.

Symposium | Future directions with novel and established BCMA-DT in the multiple myeloma treatment paradigm

Symposium | Future directions with novel and established BCMA-DT in the multiple myeloma treatment paradigm

Future directions with novel and established B-cell maturation antigen (BCMA)-directed therapies in the multiple myeloma (MM) treatment paradigm were presented by Maria Victoria Mateos at the recent Multiple Myeloma Hub symposium.

This independent educational activity was supported by GSK. All content was developed independently by SES in collaboration with the faculty. The funder was allowed no influence on the content of this activity.