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Which targets are being explored in myeloma with bispecific antibodies?

Featured:

Ajai ChariAjai Chari

Jun 15, 2022

Learning objective: After reading this article, learners will be able to cite a new clinical development in multiple myeloma.


During the 8th World Congress on Controversies in Multiple Myeloma (COMy), the Multiple Myeloma Hub was pleased to speak to Ajai Chari, Icahn School of Medicine at Mount Sinai, New York, US. We asked, Which targets are being explored in myeloma with bispecific antibodies?

Which targets are being explored in myeloma with bispecific antibodies?

Chari begins by explaining the benefits of bispecific antibody therapies, such as their "off-the-shelf" use, as well as the potential to use them in patients with comorbidities. Chari goes on to discuss three targets of bispecific antibodies; BCMA, GPRC5D, and FcRH5.