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Combining bispecific antibodies with monoclonal antibodies to treat relapsed/refractory MM

Apr 22, 2022
Learning objective: After reading this article, learners will be able to cite a new clinical development in relapsed/refractory MM

During the 3rd European Myeloma Network Meeting, the Multiple Myeloma Hub was pleased to speak with María-Victoria Mateos, University Hospital of Salamanca, Salamanca, ES. We asked, How can bispecific antibodies be combined with monoclonal antibodies to treat relapsed/refractory multiple myeloma?

Combining bispecific antibodies with monoclonal antibodies to treat relapsed/refractory MM

Mateos begins by giving an overview of the bispecific antibodies, talquetamab and teclistamab. These antibodies have been investigated in combination with daratumumab in two clinical trials; Mateos provides a summary of the results of these trials, including the safety and efficacy data.