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2024-07-22T12:48:03.000Z

Infections associated with bispecific antibodies

Jul 22, 2024
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Learning objective: After reading this article, learners will be able to cite key considerations regarding infections associated with bispecific antibodies for the treatment of multiple myeloma.

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During the Multiple Myeloma Hub Steering Committee Meeting in May 2024, leading experts met to discuss key considerations regarding infections associated with bispecific antibodies.

Infections associated with bispecific antibodies

Meral Beksaç opened with a presentation reviewing the infectious complications associated with bispecific antibodies and current treatment algorithms for such infections. Beksaç explored an analysis of infections and parameters of humoral immunity in the MonumenTAL-1 study, the clinical management of infections, and regional differences in access to prophylaxis and treatment for infections.

Infections associated with bispecific antibodies (Q&A)

Following her presentation, Beksaç chaired a Q&A session featuring Hermann Einsele, Heinz Ludwig, María-Victoria Mateos, Paul Richardson, Vania Tietsche de Moraes Hungria[JD1] [LN2] [JD3] , and Elena Zamagni[LN4] [JD5] [JD6] . Discussions included the challenges associated with COVID infections, the need for vaccination of donors for intravenous immunoglobulin treatment, and the impact of dosing schedules on reducing infectious complications and T‑cell exhaustion.

Infections associated with bispecific antibodies

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