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At the 24th Congress of the European Hematology Association (EHA), Charlotte Pawlyn from the Institute of Cancer Research, London, UK, presents a subgroup analysis of carfilzomib, cyclophosphamide, lenalidomide, and dexamethasone (KCRd) induction by molecular risk from the Myeloma XI study.
Dr. Pawlyn introduces the Myeloma XI trial which evaluated more than 4000 newly diagnosed transplant eligible patients with MM in 110 National Health Service (NHS) centers. The subgroup analysis of a patient population with genetic mutations showed similarly superior progression-free survival (PFS) with quadruplet, rather than triplet, therapy.