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What are the pros and cons of bispecific antibodies for multiple myeloma?

Jul 29, 2022
Learning objective: After reading this article, learners will be able to cite a new clinical development in multiple myeloma.

During the ASCO 2022 Congress, the Multiple Myeloma Hub was pleased to speak to Roberto Mina, University of Turin, Turin, IT, and Andrzej J. Jakubowiak, The University of Chicago, Chicago, US. We asked, What are the pros and cons of bispecific antibodies for multiple myeloma? 

What are the pros and cons of bispecific antibodies for multiple myeloma?

Mina and Jakubowiak discuss the MajesTEC-1 and MagnetisMM-1 trials, the efficacy and response rates of bispecific antibodies, and the challenges of using bispecific antibodies, such as infection risk. They also compare bispecific antibodies to CAR T-cell therapies and talk about the sequencing of therapies in myeloma treatment.

This educational resource is supported through funds from pharmaceutical companies; a full list of our supporters can be found at All content is developed independently by SES in collaboration with the faculty. The funders are allowed no influence on the content of this resource.



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