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During the American Society of Clinical Oncology (ASCO) Annual Meeting, the Multiple Myeloma Hub was pleased to speak to Cristina Gasparetto, Duke University Cancer Center, Durham, US. In this video, she discusses the potential of selinexor combinations for relapsed/refractory multiple myeloma.
Cristina Gasparetto describes the mechanism of action of selinexor and the previous STORM study, which resulted in high toxicities. She then describes the results from the ongoing STOMP study that is comparing selinexor in combination with other backbone treatments. Dr Gasparetto describes the patient outcomes of the selinexor, dexamethasone and daratumumab arm and the selinexor, dexamethasone and carfilzomib arm. She also talks about the new dosing regimen that led to better tolerability and she concludes by discussing the response rate, progression-free survival and overall response rates.
The potential of selinexor combinations for RRMM
Clinical Advances in Myeloma 2018 | Treatments for newly diagnosed and relapsed patients
A summary of two talks from the second session of Clinical Advances in Myeloma 2018 explorijng treatment options for NDMM and RRMM.treatments, especially for...
How to treat first relapse in lenalidomide-refractory MM?
During the 2021 ASCO Annual Meeting, the Multiple Myeloma Hub spoke with Clifton C. Mo and Omar Nadeem, Dana-Farber Cancer Institute, Boston, US. We asked, How to treat first relapse in...
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