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Updated data from the phase II KarMMa-2 trial
Updated data from the phase II KarMMa-2 trial
At the European Haematology Association Congress 2024, Xavier Leleu, Poitiers University Hospital, Poitiers, FR discussed results from Cohort 2B of the phase II KarMMa-2 trial (NCT03601078) investigating the safety and efficacy of idecabtagene vicleucel (ide-cel) in patients with clinical high-risk early-relapse multiple myeloma without frontline stem cell transplantation (N = 31). The primary endpoint of complete response rate was achieved in 71% patients, highlighting the potential for ide-cel use in earlier lines of treatment.
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What is the most significant limitation you have identified when using lenalidomide or pomalidomide for the treatment of patients with multiple myeloma?