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In which scenarios a PI added to Rd maintenance could benefit patients with MM after auto-HSCT?

Featured:

María-Victoria MateosMaría-Victoria Mateos

Jan 28, 2022


During the 63rd ASH Annual Meeting and Exposition, the Multiple Myeloma Hub was pleased to speak to María-Victoria Mateos, University Hospital of Salamanca, Salamanca, ES. We asked, In which scenarios a protease inhibitor (PI) added to lenalidomide-dexamethasone (Rd) maintenance could benefit patients with multiple myeloma (MM) after autologous hematopoietic stem cell transplantation (auto-HSCT)?

In which scenarios a PI added to Rd maintenance could benefit patients with MM after auto-HSCT?

In this video, Mateos discusses the phase III GEM2014MAIN trial (NCT02406144) conducted by the Spanish Myeloma Group (GEM). The trial investigated ixazomib plus lenalidomide-dexamethasone (IRd) versus lenalidomide-dexamethasone (Rd) maintenance after auto-HSCT in patients with newly diagnosed MM.