All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional. If you are a patient or carer, please visit the International Myeloma Foundation or HealthTree for Multiple Myeloma.

The Multiple Myeloma Hub uses cookies on this website. They help us give you the best online experience. By continuing to use our website without changing your cookie settings, you agree to our use of cookies in accordance with our updated Cookie Policy

Introducing

Now you can personalise
your Multiple Myeloma Hub experience!

Bookmark content to read later

Select your specific areas of interest

View content recommended for you

Find out more
  TRANSLATE

The Multiple Myeloma Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the Multiple Myeloma Hub cannot guarantee the accuracy of translated content. The Multiple Myeloma Hub and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.

Steering CommitteeAbout UsNewsletterContact
LOADING
You're logged in! Click here any time to manage your account or log out.
LOADING
You're logged in! Click here any time to manage your account or log out.

The Multiple Myeloma Hub is an independent medical education platform, sponsored by Bristol Myers Squibb, GSK, Johnson & Johnson, Pfizer, Roche and Sanofi. The levels of sponsorship listed are reflective of the amount of funding given. Digital educational resources delivered on the Multiple Myeloma Hub are supported by an educational grant from Janssen Biotech, Inc. View funders.

2021-07-02T08:51:04.000Z

How do MM cells develop resistance to BCMA-targeted agents? Can it be overcome in the clinic?

Bookmark this article

During the EHA2021 Virtual Congress, the Multiple Myeloma Hub spoke with Leo Rasche, University Hospital of Würzburg, Würzburg, DE. We asked, How do multiple myeloma cells develop resistance to B-cell maturation antigen (BCMA)-targeted agents? Can it be overcome in the clinic?

In this video,  Rasche discusses the recent discovery of a resistance mechanism to anti-BCMA therapies, which include both bispecific antibodies and chimeric antigen receptor T-cell therapies.

For more information about BCMA-resistance mechanisms, read our latest review here.

 

Your opinion matters

Which dosing schedule for belantamab mafodotin do you think is optimal for providing an efficacy benefit while managing toxicities?
2 votes - 42 days left ...

Newsletter

Subscribe to get the best content related to multiple myeloma delivered to your inbox