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How can we identify early the best responders to ide-cel?

Jan 20, 2023
Learning objective: After reading this article, learners will be able to cite a new development in the monitoring of multiple myeloma.

During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the Multiple Myeloma Hub was pleased to speak to Bruno Paiva, University of Navarra, Pamplona, ES. We asked, How can we identify early the best responders to idecabtagene vicleucel (ide-cel)?

How can we identify early the best responders to ide-cel?

In this interview, the results of the KarMMa phase II clinical trial are discussed, as presented at the 64th ASH Annual Meeting and Exposition. Paiva examines measurable residual disease (MRD) compared with serological response following ide-cel and the ideal timepoint for assessing depth of response. Paiva concludes by describing the relationship between early undetectable MRD following ide-cel infusion and progression-free survival in patients with relapsed/refractory multiple myeloma.