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What are the management strategies for CRS and ICANS in MM?
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During the 65th American Society of Hematology (ASH) Annual Meeting and Exposition, the Multiple Myeloma Hub spoke to Hermann Einsele, Julius-Maximilians-Universität Würzburg, Würzburg, DE. We asked, What are the management strategies for cytokine release syndrome and immune effector cell-associated neurotoxicity in multiple myeloma?
What are the management strategies for CRS and ICANS in MM?
Einsele discusses the management of cytokine release syndrome and immune effector cell-associated neurotoxicity in patients treated with common immunotherapies such as chimeric antigen receptor T cells and bispecific antibodies. He then outlines the incidence and risk factors associated with immune-mediated toxicities from these immunotherapies. Finally, Einsele concludes by exploring several therapeutic strategies, including the use of bridging therapies, prophylactic steroids, and supportive care.
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