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The Multiple Myeloma Hub is an independent medical education platform, sponsored by Bristol Myers Squibb, GSK, Pfizer, Roche and Sanofi. The levels of sponsorship listed are reflective of the amount of funding given. Digital educational resources delivered on the Multiple Myeloma Hub are supported by an educational grant from Janssen Biotech, Inc. View funders.

2023-07-14T14:15:01.000Z

Is upfront auto-SCT still the preferred option for eligible patients?

Jul 14, 2023
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Learning objective: After reading this article, learners will be able to cite a new clinical development in multiple myeloma.

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The Multiple Myeloma Hub was pleased to speak to Sergio Giralt, Memorial Sloan Kettering Cancer Center, New York, US. We asked, Is upfront auto-stem cell transplant (SCT) still the preferred option for eligible patients?

Is upfront auto-SCT still the preferred option for eligible patients?

Giralt shares data from the IFM2009 (NCT01191060) and DETERMINATION (NCT01208662) clinical trials comparing patients who received induction therapy with and without upfront transplant. Giralt considers the latest follow-up data on progression-free survival and measurable residual disease-negativity rates between cohorts as factors, as well as the impact of individual patient factors such as preference, risk status, and age on selecting upfront auto-SCT.

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