General MM

How to overcome resistance to CAR T in patients with multiple myeloma?

L: English

During the 2nd European CAR T Cell Meeting in Sitges, ES, the Multiple Myeloma Hub was delighted to speak to Ibrahim Yakoub-Agha from Lille University Hospital, Lille, FR. We asked: How to overcome resistance to CAR T in patients with multiple myeloma?

Ibrahim Yakoub-Agha explains that understanding the factors that are associated with myeloma resistance such as the microenvironment will help in the development of effective CAR T cells. He explains the identification of target antigens has seen some success in the myeloma field.